Empowered ISOs are a powerful type of ISO in Marvel: Avengers Alliance that, when attached to a hero, effectively grants the powers of an alternate uniform to that character. This is particularly intriguing because high enough level heroes can even add one of these ISOs to an alternate uniform, adding two total special abilities beyond the base abilities of that hero. Character specific E-ISOs are earned by successfully completing heroic battles in season 2. Not all empowered ISOs are made evenly though and some heroic battles are much more difficult than others. The following guide to character specific empowered ISOs in chapter 5 of season 2 of Marvel: Avengers Alliance will help you determine whether specific ISOs are worth the time and energy to acquire.
Resolute E-ISO, Thundra, Mission 1 (A-) – The Resolute ISO suppresses just about any effect that prevents or removes buffs on Thundra. This is exceptionally useful in PvP, but rarely comes up in PvP. The problem with that is that Thundra is not even really a second string PvP character. Still, the effect will occasionally help in PvE and this heroic battle is so easy, that it is worth the effort to get this ISO.
Furious E-ISO, She-Hulk, Mission 1 (B) – She-Hulk is one of the five worst heroes in the game. This E-ISO doesn’t even make her a second stringer, but it brings her out of the trash pile. While equipped, she gains a stack of Hulk Up each round and when attacked. Unlike Hulk, she never spends them, so she just quickly gains a permanent damage boost. This does nothing to resolve her accuracy issues nor fixes her incredibly vanilla power set, but she actually becomes reasonably good at dealing damage.
Predatory E-ISO, Tigra, Mission 1 (B+) – This ISO grants Tigra a chance to follow-up with Swipe when she makes a single target attack. The extra attack seems nice, but it can waste the benefit of Sharpened Claws when you might prefer to use it on a more powerful attack. In general, though, extra damage is good and Tigra will use single target attacks during most rounds.
Aromatic E-ISO, X-23, Mission 2 (D-) – Aromatic E-ISO causes trigger scent to activate when X-23 attacks an enemy if it isn’t already active on an enemy. The only saving grace for this ISO is that it will highly increase X-23’s damage when it activates. But this also means that you are forced to attack that enemy until it is defeated. X-23 is already hard to control and this just makes her worst 9 times out of 10. It is only because of those rare times when this is actually an advantage that this ISO isn’t a complete failure.
Draconian E-ISO, Kitty Pryde, Mission 1 (A) – Whenever Kitty Pryde is attacked, while she is not phased, Lockheed automatically counters. Given his low counter rate, this is a nice boost. It won’t come up much since she usually spends over half of a battle phased, but the benefit is always good, except against the rare opponent that heals from fire. If the battle to earn this ISO were a little less difficult, it would be perfect.
Pyroclastic E-ISO, Human Torch, Mission 3 (C+) – The benefit from Pyroclastic is actually rather trivial. Attacks against burning targets apply pyrophoric and attacks against targets with pyrophoric apply melt armor. While this sounds good, Human Torch deals such high damage that you will rarely gain the second benefit in a battle. Still, the benefit is purely positive and very easy to take advantage of. Assuming you own Thing and Invisible Woman and they are each at least level 6 and level 9 respectively, this is an easy enough battle to probably be worth your time, barely.
Masonic E-ISO, Thing, Mission 3 (B+) – Thing is far from the best hero in the game, or even the best protector hero in the game, but when you need him in battle, you almost always need him to use Stone Wall constantly. This ISO causes him to start the battle with it already activated and for him to take reduced damage while Stone Wall is active. It is exactly the benefit you want during the rare times you use Thing. Unfortunately, you have to own to other second string heroes to actually get the Masonic empowered ISO.
Circulating E-ISO, Invisible Woman, Mission 3 (A+) – Circulating E-ISO is the reason to fight this battle again and again. It is a top tier ISO normally and just about perfect when attached to the Future Foundation alternate costume. Whenever a team mate is affected by one of Invisible Woman’s shields, all negative status effects are removed and the teammate is immune to new applications. This is a major boost for Force Field and is nearly broken with Reactive Shields.
Dynamo E-ISO, Bishop, Mission 4 (A+) – There are two reasons this ISO is so good. First, Bishop gains an extra potential energy whenever he uses one of his Run and Gun powers. This increases the speed of his combos and makes him much more powerful overall. Second, this heroic battle is practically trivially easy because Bishop basically can’t die during it. If you ever use this hero, this is an ISO worth owning.
Grounding E-ISO, Havok, Mission 4 (B-) – Grounding E-ISO causes Havok to protect allies from energy attacks. Since he takes half damage from these attacks, this is modestly good, but Havok is a hero you generally want to protect, not one you want protecting your team. It is probably safe in PvE, though you will generally want to avoid using this ISO in PvP. Additionally, this ISO actually makes this particular heroic battle harder, rather than easier. So, if you are still trying to get Dynamo, do not equip this ISO.
Duplicitous E-ISO, Fantomex, Mission 5 (F) – Fantomex is a terrible character and this ISO offers a benefit that is unnecessarily specific and only functions based on a specific power from his set. Whenever an enemy attacks another enemy, Fantomex will follow-up that attack. Fantomex can apply disoriented with Fantome, but even when you use this power, enemies will attack each other less than half the time. You could build a team based on taking advantage of this, but it isn’t worth your time since Fantomex is pretty much a waste of space on any team. If you get the ISO, equip it, but it isn’t worth any effort to get.
Synchronized E-ISO, Psylocke, Mission 5 (B) – Synchronized causes your team to start every battle with Mental Coordination active. This saves Psylocke an action and lets the team start attacking together earlier in the battle. It is a great effect in PvE, but less useful in PvP where it will probably be removed, at which point the ISO is entirely worthless.
Rhythmic E-ISO, Spiral, Mission 5 (A+) – Spiral was already an excellent character, especially in boss battles, and this just makes her a lot better. All dance actions are available as a multi-action, rather than having to unlock them by using specific moves. This greater flexibility removes the one major frustration with this character and easily puts her in the top tier of heroes in the game. As an added benefit, this battle is easy enough that you shouldn’t have difficulty farming for this ISO.
Smoldering E-ISO, Red Hulk, Mission 6 (D) – Smoldering E-ISO causes Red Hulk to start with 40% heat. More often than not, this is actually a detriment rather than an advantage. Red Hulk already builds up heat very quickly, especially when he is being used to protect with Bulwark, and meltdown is very bad for him. There are some battles where you will want the early heat, but very few.
Ironclad E-ISO, Hulk, Mission 6 (A) – The only downside to this E-ISO is that Thick is also a really good E-ISO and you can’t equip both on Hulk if he is wearing an alternate costume. Ironclad has a chance to reduce damage and prevent critical hits. The benefit is better than Thick when it activates, but Thick is more consistent. Combined on the base Hulk costume, this turns Hulk into a much more damage resistant character than normal. Unless you are using an alternate costume and absolute insist on using Thick, this is a great ISO for Hulk.