Empowered ISOs are a special type of ISO in the Facebook game Marvel: Avengers Alliance that does not provide boosts to stats. Instead they provide a static special ability to the character equipped. Each hero gains one E-ISO slot at level 4 and another at level 13 in their primary costume or only one at level 13 in an alternate costume. Generic empowered ISOs can be purchased in the store, but, with only three exceptions, character specific E-ISOs must be won from heroic battles. These battles are often difficult and take a lot of energy to attempt. The following guide to empowered ISOs in season 2 chapter 1 of Marvel: Avengers Alliance will help you determine if they are worth the effort.
Pilfered E-ISO, Gambit, Mission 1 (A) – The Pilfered ISO grants Gambit the ability to gain eight stacks of kinetic charge, rather than the normal four. Given how often Gambit earns stacks off-turn, this is an excellent benefit that will be regularly useful. The heroic battle is rather easy, especially if you have the alternate outfit for Rogue and the energy cost to attempt the battle is low.
Caressing E-ISO, Rogue, Mission 1 (C+) – The first action Rogue usually takes in any battle is to attack with Southern Comfort in order to gain an additional action in the following round. This means that the only meaningful benefit she gets from starting with Into the Fray is increased damage on her first attack. It is a rather trivial benefit. If you don’t have a better E-ISO to give her, it is fine, but nothing to write home about.
Soothing E-ISO, Wolverine, Mission 2 (D+) – The benefit of this ISO is good on paper, but it is extremely hard to use effectively. It will heal Wolverine completely once per battle as an action. Unfortunately, this is difficult to use effectively in most battles, unless you get lucky on timing of character actions. A mediocre benefit is made even worse by a battle that takes an entire energy bar to reach.
Frenzied E-ISO, Sabretooth, Mission 2 (B+) – Frenzied is a first class ISO, but the energy requirement to reach this battle makes it annoying to try to acquire. If you do get it, Sabretooth starts in a frenzied state, which means he acts twice a round and heals about four times as much as normal each round. He can’t resurrect like normal, but he is much less likely to need that resurrection. It is an amazing benefit that makes him even more of a powerhouse character.
Revered E-ISO, Nightcrawler, Mission 3 (B) – Revered was a better ability before the mystic shroud ability could be removed. Now it is simply mediocre. It will generally help in short PvE battles, but will only have minor benefits in most PvP battles or boss fights. The energy cost to attempt this battle is rather low, though the battle itself is difficult unless you have the Nightcrawler alternate costume. Worth your time if you primarily want Nightcrawler for PvE.
Tantalizing E-ISO, Spider-Woman, Mission 4 (F) – This ISO makes the mind control status effect from Seduction Pheromones last an additional round. This status effect already lasts two rounds, which is generally long enough. Additionally, once it is triggered, it goes away. Overall, you will generally get almost no benefit from this special ability, and you will have to spend almost an entire energy bar to get it.
Smiting E-ISO, Hercules, Mission 5 (A+) – This is one of the best empowered ISOs in the game. When Hercules is attacked by an area attack, he has a high chance of countering with Column Down. Column Down grants strengthened to Hercules and has a chance to stun all enemies. It is a great attack on its own. The fact that this can also increase the speed that Hercules gains Blessing of Olympus and stacks with counterattacks from Gift of Battle just makes it a brilliant ability. The best part about farming for this ISO is that it only takes 30 energy to attempt and this is the easiest heroic battle in the game.
Instant E-ISO, Cable, Mission 6 (B) – The Instant E-ISO is a great ISO, but it is very hard to get. You need to own Cable, Deadpool, and Gambit, must spend almost an entire energy bar in the attempt, and the battle is painfully hard. If you manage to get it, the benefit is worth the effort. Cable will have a chance of preemptively countering any attack against him.
Spicy E-ISO, Deadpool, Mission 6 (B-) – It takes the same effort to get this ISO as it does to get Instant E-ISO for Cable and this one is not quite as good. It will resurrect Deadpool to half health the first time he is defeated in a battle. It is a nice benefit, but one that will rarely come up in PvE and one that can be countered many ways in PvP.