Many of the chapters in season 2 of Marvel: Avengers Alliance drop excellent character specific empowered ISOs, but chapter 4 drops some of the best. Not only does it have solid E-ISOs, but many of the battles to get them are reasonably easy. They do tend to be energy intensive to attempt, so you may want to pick and choose carefully which are most important to you. If you are farming character specific empowered ISOs in season 2 chapter 4 of Marvel: Avengers Alliance, this guide will help you determine which are the best to hunt.
Fluxing E-ISO, Magneto, Mission 1 (C) – The benefit from the Fluxing E-ISO is mediocre at best. It makes it impossible for magnetized to be prevented or removed. Since Magneto is constantly applying this status effect anyway, that is a rather minor benefit. Additionally, you have to own Emma Frost to complete this battle, not Magneto. The one major redeeming quality of this battle is that it is quite easy to win.
Eternal E-ISO, Emma Frost, Mission 1 (A+) – There is nothing better than an empowered character specific ISO that potentially lets a character drastically reduce all damage from all attacks. By causing Diamond Body to no longer trigger organic recovery, that is exactly what the Eternal ISO does. It arguably makes Emma Frost completely broken and makes this a great battle to farm.
Thick E-ISO, Hulk, Mission 2 (B) – With this ISO equipped, each hulk up reduces damage to Hulk. It is a solid benefit that actually helps with one of this hero’s weaknesses. The heroic battle is rather difficult, though, so you may not want to put too much effort into getting it, given that there are other empowered ISOs that you can simply purchase to make Hulk more durable.
Berserking E-ISO, Sif, Mission 3 (F) – This ISO grants Sif, at the start of every battle, the same berserker buff that Sabretooth can apply to himself. Unlike Sabretooth, she can’t reapply the buff and the buff can be removed. Additionally, the battle to acquire it is painfully luck driven and no fun at all. There is absolutely no reason to try to acquire this.
Windy E-ISO, Storm, Mission 4 (A) – This heroic battle is quite difficult, though made considerably easier if you have even one alternate costume. Since all three heroes have alternate costumes, your chance of having one is greatly increased. The Windy E-ISO provides an excellent general benefit and happens to make this battle a lot easier if you are trying to acquire the other two ISOs. Equipped, it grants protective shroud at the start of the battle. If you can get it, make sure to equip it immediately.
Decimating E-ISO, Colossus, Mission 4 (A-) – The benefit of this ISO is nearly as great as Windy, but Colossus isn’t as good a character as Storm. Equipped, Decimating grants this hero a chance to counter attacks with Decimate. It is a large damage increase for a character that generally isn’t so great in that category.
Commanding E-ISO, Cyclops, Mission 4 (A-) – Every single E-ISO is worth it in this battle, making it one of the best heroic battles in the game to fight repeatedly. Once equipped, Cyclops gains the Inspiring Leadership special ability of Captain America. This stat boost stacks with the Morale Boost he can grant allies. As long as you don’t team him with Cap, this is an amazing benefit, though frustratingly, the least helpful of the three for this particular heroic battle.
Knightly E-ISO, Captain Britain, Mission 5 (B+) – The benefit from Knightly isn’t spectacular. All it does is increase the chance of Captain Britain taking reduced damage when Roar of Valor is active. But, the heroic battle is so easy it is almost trivial. Britain is a good enough hero that it is worth at least a modicum of effort.
Predictive E-ISO, Mockingbird, Mission 6 (A+) – Predictive is arguably the best character specific empowered ISO in the game by a far margin. It makes Mock Combat activate before Mockingbird is attacked, which means she is always the counter class of any enemy attacking her. She counters all tacticians, gets enraged from all scrappers, and gains an extra turn from all blasters. Additionally, she will receive fewer critical hits and lower damage overall. This battle is reasonably easy, which makes this worth all the time and effort you put into it.